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Dapoxetine and Combination Drugs
9 Dec. 2013

dapoxetine-coupleDapoxetine is one of the most often used drugs today for treatment of premature ejaculation (PE) in men. This medicine was first developed as an antidepressant, as it belongs to the selective serotonin reuptake inhibitor (SSRI) family of drugs. These chemicals regulate the amount and action of serotonin, a special substance naturally occurring in the human central nervous system and considered to be responsible for mood and feeling of happiness, among other things. It has also been found out that modulation of serotonin at brain synapses can be used to treat PE. There have been many other SSRI antidepressants that have been proposed as suitable medication for the condition. However, dapoxetine boasts one major advantage over the other substances from its family – after the desirable effect has been achieved, the drug is rapidly metabolized and its products are fully eliminated from the body within several days.

The half-life of the process (the time needed for the amount of the drug in the system to decrease in half) does not exceed 22 hours. This gives dapoxetine an advantage over other SSRI drugs, making it suitable for PE treatment with no risk of drug accumulation in the body when daily doses are required by the patient. Curiously enough, the rapid elimination of dapoxetine from the organism makes it incapable of acting as an antidepressant for which it was originally created.

How should Dapoxetine be taken?

To be effective, dapoxetine has to be taken several (2 to 3) hours prior to the planned sexual activity. Daily usage is necessary to successfully treat PE. Think of dapoxetine as a drug that you take when you need to, rather than a pill that will cure the condition once and for all. According to clinical studies, depending on the dose of the drug taken and various other conditions, the use of dapoxetine can increase the length of the intercourse up to 3-4 times. The drug also enhances the personal feeling of control during the sexual act, improves the feeling of satisfaction and is subjectively judged by patients as diminishing their personal distress concerning their condition. There are no grave adverse effects shown for this medication. 11% to 22% of patients report feeling slight nausea after taking the drug, 10% suffer from dizziness or headache; indigestion and insomnia happen in less than 10% of the cases. Dapoxetine can also be taken safely with alcohol as well as with drugs that are prescribed for treatment of erectile dysfunction, chiefly tadalafil and sildenafil (better known as Cialis and Viagra).

Dosage of Dapoxetine

Dapoxetine is marketed under the brand name Priligy by Johnson & Johnson. It usually comes in tablets containing 30 mg or 60 mg of the active ingredient. 30 mg before the planned sexual activity is usually enough for most patients to alleviate their condition. The step up to 60 mg results in the slight increase in the drug’s effect and might be desirable for some patients.

prilygy-logoCombination drugs that use Dapoxetine

There also exist other drugs that contain dapoxetine. Some of them, like Super P-Force and Super Hardon, combine dapoxetine with other active ingredients aimed at treating erectile dysfunction, such as sildenafil (which is used in Viagra, for example). Such a combination of drugs is proven to be absolutely safe and quite effective at treating both conditions at once, as there’s no interaction between the two. You should consult your doctor to better gauge the extent of any sexual dysfunctions so that you might be able to find the best solution for your particular case.

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