Generic Coversyl 4 mg
Coversyl is an ACE inhibitor that treats hypertension, cardiac failure and ischemic heart disease. 4 mg once daily is a usual dose for essential hypertension management and a starting dose for ischemic heart disease. The dose may be then up-titrated as to drug acceptability and therapeutic response. The drug may also prevent diabetic nephropathy, ventricular hypertrophy and left ventricular systolic dysfunction.
What is Coversyl?
Coversyl is an ACE inhibitor in the form of perindopril arginine. It is applied in hypertension, coronary artery disease (CAD) and cardiac insufficiency treatment. The agent works by stopping the action of angiotensin-converting enzyme, allowing blood vessels to relax and dilate. Consequently, blood pressure reduces, heart doesn’t have to work so hard to pump blood, and therefore heart failure symptoms are improved. The medicine is produced in tablet form and is available under several trade names.
When is Coversyl indicated?
Coversyl is indicated for treatment of essential hypertension, CAD and symptomatic heart failure. The medicine reduces risk of cardiac events in adults with a previous history of cardiac infarction and revascularization. It is not approved for use in children.
How to take Coversyl?
Coversyl should be started with a small dose of 4 mg for adults and 2 mg for geriatric patients, which can be altered after several weeks of treatment with the drug. The usual dose for essential hypertension is 4 mg q24h or 4 mg q12h. The initial dose for CAD is 4 mg q24h, with possible further up-titration to 8 mg q24h, depending on tolerability and response. Congestive heart failure should be treated with 2 mg q24h under the strict care of a physician. Later, the dose can be raised to 4 mg q24h.
What are Coversyl side effects?
Coversyl mild side effects, which usually manifest at the beginning of treatment, are: cough, headache, fatigue, asthenia, and sleep and mood disturbances. In rare cases it can provoke, taste impairment, abdominal pain, nausea, epigastric discomfort and rash. Very rarely it may lead to edema, hypotension, proteinuria, hypochromia, decreased red blood cells and platelet count.
When is Coversyl contraindicated?
Coversyl is contraindicated to children, breastfeeding and pregnant women and adults with idiopathic or hereditary angioneurotic edema. It shouldn’t be used by people with hypersensitivity to tert-butylamine salt of perindopril and people with rare hereditary illnesses as lactase deficiency, galactose intolerance or glucose-galactose malabsorption. The drug is administered with caution to people with decreased kidney or liver function.
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