Generic Macrobid 50 mg
This antibacterial drug is primarily used to treat bladder and urinary tract infections caused by several types of bacteria. It is a potent antibiotic when used to treat appropriate types of bacteria, but should not be utilized for kidney infections or other types of infections.
What is Macrobid?
Containing nitrofurantoin in form of crystals and nitrofurantoin monohydrate, the drug is an efficient antibacterial agent versus several strains of harmful bacteria responsible for urinary tract and bladder infections. The drug works by attacking various parts of the bacterial cell, including its DNA, suppressing their functioning and growth.
What are the indications for using Macrobid?
This drug is used specifically to treat the bacterial urinary tract infections – the acute cystitis, which is caused by particular strains of bacteria, namely Escherichia coli and Staphylococcus saprophyticus. This type of antibiotic is not used for other types of infections, including kidney infection (pyelonephritis) or other tissue or organ infections. It is recommended to only use the antibiotic treatment when the cause of the infection is established to be one of the susceptible strains of bacteria.
What is the dosage of Macrobid?
The drug is provided in form of capsules containing an equivalent of 100 mg of nitrofurantoin, 25 mg as crystals and 75 mg as nitrofurantoin monohydrate. The medication is recommended to be taken with food; two 100 mg Macrobid capsules should be taken per day, one every 12 hours. The duration of Macrobid therapy is usually one week.
What are the contraindications for using Macrobid?
The main contraindication for use of this drug is renal impairment, as well as anuria or oliguria. When metabolized in the body, the drug releases active components that, while not being as harmful to mammalian cells as to bacterial cells, can still be toxic when not excreted normally with urine. The drug is also not recommended for use by pregnant women and young children. Patients who previously had cases of liver dysfunction related to nitrofurantoin use should not take Macrobid as well.
What are the adverse effects of Macrobid?
The most common adverse effects reported by patients taking the medication are nausea, headache, and change in skin and eye color. The change of urine color is a normal temporary effect that will pass as soon as the use of the drug is stopped. However, if the change persists inform your doctor right away, as this may indicate side effects related to liver dysfunction and/or anemia.
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