What is Reglan?
Reglan is a gastroprokinetic and antiemetic drug commonly used to treat vomiting, nausea, gastric stasis and gastroparesis. Its scientific name is metoclopramide and has been known under many other names in different countries, like Clopamon, Degan, Tomit, Placin, and Maxeran. It was developed in the late half of the 20th century and became widely available in 1982, ushering in a new era of gastric health. It belongs to a class of medicines called dopaminergic blockers.
What are the indications for using Reglan?
As mentioned before, Reglan treats symptoms like nausea and vomiting, which usually stem from conditions like radiation sickness, uremia, malignancy and migraines. The medicine works by raising the frequency of muscle contractions in the digestive tract, letting the stomach empty and cleanse itself faster. Another major effect of the drug involves blocking dopamine. This is sometimes effective in stimulating lactation. Finally, Reglan also settles allodynia, helping migraines pass.
What is the dosage of Reglan?
Reglan is recommended for adult usage only. Patients suffering from Symptomatic Gastroesophageal Reflux should take from 10 to 15 mg Reglan a day over the course of 4 to 12 weeks 30 minutes before each meal and at bedtime, though this varies from patient to patient. Patients with diabetic gastroparesis should take 10 mg before meals and bedtime for a period of two to eight weeks, depending on the body’s response.
What are the contraindications for using Reglan?
You should take care to avoid mixing Reglan with certain drugs. For example, anticholinergic drugs and narcotic analgesics can counteract the gastric ease provided by Reglan. Patients using monoamine Oxidase inhibitors might want to avoid Reglan, as it has been known to release catecholamines. It’s also important to note that the effect of other drugs may be reduced as a result of Reglan.
What are the side effects of Reglan?
Recorded side effects from studies and trials include fatigue, tardive dyskinesia, hypotension, nausea, rash, and others.
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